Check Out Highlights From WIRED’s 2025 Big Interview Event

Zahra Aisyah

December 5, 2025

…’s Big Interview series prides itself on being the place for engaging conversations with political leaders, creators, executives, and scientists moving the world forward. In 2024, we brought those talks to a stage in San Francisco for the very first time. This year, we did it again, bringing together AMD CEO Lisa Su, Wicked director Jon M. Chu, Anthropic cofounder Daniela Amodei, Cloudflare CEO Matthew Prince, and many more.

What Is It?

The Big Interview, a one-day, in-person event held at The Midway in San Francisco on December 4, featured a series of in-depth, illuminating Q&As with some of the biggest names in innovation today, each led by a … journalist. We also hosted our take on a modern-day science fair, complete with hands-on demos and other fun experiences.

Speaker List

Click to view a recap of each session:

Lisa Su, CEO, AMD
Jon M. Chu, director, Wicked: For Good
Daniela Amodei, cofounder, Anthropic
Diogo Rau, chief information and digital officer, Eli Lilly (Sponsored by Omidyar Network)
Matthew Prince, CEO, Cloudflare
Eric Topol, author, Super Agers
Daniel Lurie, mayor, San Francisco
Michele L. Jawando, President, Omidyar Network (Sponsored by Omidyar Network)
Jeremy Allaire, cofounder, CEO, and chairman, Circle
David Hogg, gun-safety advocate, cofounder of March for Our Lives
Leland Dudek, former acting commissioner of the Social Security Administration, George Foote; outside general counsel to the US Institute of Peace; and Sahil Lavingia, founder and CEO, Gumroad, former DOGE software engineer
Alex Komoroske, CEO and cofounder, Common Tools, and Mike Masnick, founder and editor, Techdirt

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